Sep. 25th, 2020

(Originally posted to my GoFundMe earlier today, so I didn't bother to change the timestamp. This is basically copied verbatim (modulo formatting), including the fundraising stuff at the end; I *was* posting to GoFundMe after all. Feel free to ignore those bits if you want. Link to the fundraiser will be provided in the comments and upon request.)

It's finally time for another update in the "SARS-CoV-2/COVID-19 related PSA / traditional weblogging / usual begging post mashup" series. Today I'm coming back to pharma-chemist Derek Lowe's blog in Science Translational Medicine. I've got nearly three weeks of his blog posts to sift through, so here are the pieces I want to share in this forum. (If you want to read his other posts, feel free!)

The first one is a much more general thing but I think it's well worth a read, about trends in drug and vaccine development.

New Drugs and New Structures

The rest are more SARS-CoV-2/COVID-19 specific.

Bradykinin and the Coronavirus

Serious Adverse Event Time

The Russian Vaccine Data

Drug Repurposing: How Often Does It Work? (Ed. note: and a bit of why it does and doesn't)

Vaccine Transparency

Monoclonal Antibody Data

The Vaccine Protocols

Hey, that was only eight links! For three weeks it could have been 12 or more, but like the rest of us I suspect COVID fatigue has set in. (And he does have some truly unrelated posts as well, which are still good reads but I didn't link here.) And with that all out of the way, it's time for the usual begging part of this post. As anyone who's been reading these posts can guess, before and in addition to the usual plea for help for ourselves, I'm going to ask those of you who are able to SUPPORT YOUR LOCAL BUSINESSES. Some businesses were essential and never closed during the lockdowns. Others, after having opened back up, are now trying to stay open to what extent they can as we struggle through various phases of "reopening" including going back to more restrictions as needed. So please do what you can to help keep your local economy a little bit more afloat. Locally owned businesses are, and will continue to be, struggling to survive and get back on their feet, so please patronize them as much as you can. BUY LOCAL. Please however, do so in a safe manner. Keep on wearing masks and other protective equipment when going shopping in person, continue social distancing. Act intelligently, because I know you can.

Rest of the begging stuff is behind the cut. )

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damont

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